METABOLIC BIOCHEMISTRY

Course Learning Objectives (CLOs):

By the end of this course, MMLT students will be able to:

  1. Understand the Biochemical Pathways:

    • Describe the key metabolic pathways of carbohydrates, proteins, lipids, and nucleic acids.

    • Explain the integration and regulation of these metabolic processes in the human body.

  2. Analyze Metabolic Functions:

    • Interpret the role of enzymes, coenzymes, and intermediates in metabolism.

    • Understand the energy production and utilization through glycolysis, TCA cycle, oxidative phosphorylation, etc.

  3. Identify Metabolic Disorders:

    • Recognize inborn errors and acquired disorders related to carbohydrate, amino acid, lipid, and nucleic acid metabolism.

    • Discuss the clinical manifestations, biochemical basis, and diagnostic approach to these disorders.

  4. Perform Relevant Laboratory Tests:

    • Demonstrate practical knowledge of lab techniques to assess metabolic functions.

    • Conduct and interpret biochemical tests such as blood glucose tests, diabetic profile, lipid profile, protein estimation, and GTT.

  5. Correlate Biochemistry with Clinical Conditions:

    • Correlate metabolic abnormalities with pathophysiological conditions like diabetes mellitus, phenylketonuria, Gaucher’s disease, etc.

    • Apply biochemical knowledge to diagnose and monitor metabolic disorders in a clinical laboratory setting.

  6. Evaluate Diagnostic Results:

    • Critically analyze biochemical test results to differentiate between normal and abnormal metabolic states.

    • Suggest further biochemical or molecular investigations based on initial lab findings.

  7. Develop Research Insight:

    • Encourage analytical thinking for research-based learning on metabolic diseases.

    • Foster skills in reporting, documenting, and interpreting biochemical lab results in a clinical or research setup.